Heterochromia or Dogs with Different Colored Eyes

Heterochromia is the condition in which you see dogs with different colored eyes. This condition can be found among not only canines, but humans, cats, and horses too. It is often hereditary, although it can be the result of trauma or disease to the eye as well. Heterochromia is caused when there is a lack of pigment melanin in all or part of one eye.

It is rare to see dogs with different colored eyes

Most dogs with hereditary heterochromia do not have any related health problems. However, acquired heterochromia can be a symptom of several eye conditions. If you notice your dog’s eye color changing, it is important to get them checked by a veterinarian.

Different Types of Heterochromia

There are three types of heterochromia:

  • Heterochromia iridis – This is sometimes referred to as complete heterochromia. One eye is an altogether different color than the other.
  • Central heterochromia – The blue coloring, or lack of pigment, radiates out from the pupil and mixes with another color. In the case of dogs, it would be brown.
  • Sectoral heterochromia – The iris is only partially blue or without pigment. This type would present in two colors within one eye.

Instances of two different colored eyes are rare. Dogs with different colored eyes are not limited to specific breeds. It is possible for any type of dog to be born with two different colored eyes. However, this condition is more prevalent among certain breeds than others.

Dogs With Different Colored Eyes

Australian Shepherd

Australian shepherd with heterochromia

Australian Cattle Dog


Border Collie

Border collie with heterochromia


Dalmatian  These dogs with different colored eyes have a higher prevalence of deafness among them.

Dalmatian with two different colored eyes

Great Dane

Shetland Sheepdog

Siberian Husky

Siberian husky with heterochromia

Dogs with different colored eyes, or heterochromia, is unique and memorable. In most cases, it is not a cause for alarm. It’s just a topic of conversation next time you are at the dog park!

PlexiDor Dog Doors supports regular visits with your vet for pet wellness and staying current with your pet’s vaccines and other regular health maintenance.